Best practice advice is to control exposure to styrene to a level below the workplace exposure limit (WEL). References. J Med Toxicol. 2010. This includes monitoring for styrene-related cancers and tumors. Exposure to noise (<85 dBA p = 0.0001; ≥85 dB(A) p = 0.0192) interacted significantly with styrene exposure. Published 1 July 2014 Last updated 16 … On exposure to lig ht and air, styrene slowly undergoes polymerization and oxidation with format ion of peroxides. Exposure to styrene in air can also irritate the eyes, nose and throat. 1994, Kolstad et al. It has been reported that 60-70% of the inhaled gas is rapidly absorbed by the liver and lung tissues. 1. higher levels of styrene exposure or longer times since first exposure (Kogevinas et al. Thus, employers should make every effort to maintain exposure concentrations as low as possible. According to scientists, inhalation of styrene gas is the major route of exposure in humans. Atlanta, GA: Centers for Disease Control and Prevention. Eye Protection: ... (104F) to form a heat-sensitive explosive peroxide. Styrene can enter the environment after being released by the manufacturer in the form of a gas or liquid. with all sections of the recommended standard should prevent or greatly reduce the risk to exposed workers of adverse effects. Health effects of styrene include irritation of the skin, eyes, and the upper respiratory tract. How does styrene gas affect the body? Exposure to high concentrations of styrene in air can affect the central nervous system causing tiredness, muscle weakness, problems concentrating and nausea. 1994). Acute exposure may also result in gastrointestinal effects. Although co-exposure to butadiene is a concern in the styrene-butadiene industry, the find-ing of increased cancer risk in the reinforced-plastics industry, where NIOSH considers the recommended environmental limits for styrene to be upper boundaries of exposure. Acute (short-term) exposure to styrene in humans results in mucous membrane and eye irritation, and gastrointestinal effects. Results: The median current styrene exposure was 53.6 mg/g creatinine (interquartile range: 19.5-94.4). Acute (short-term) exposure to styrene in humans results in mucous membrane and eye irritation, and gastrointestinal effects. He said chronic (long-term) exposure to styrene … Signs and symptoms of Styrene exposure. Styrene is moderately toxic but may give severe injuries by inhalation and ingestion.and long term exposure is fatal. Styrene may cause cancer, though it is still unknown. Agency for Toxic Substances and Disease Registry (ATSDR). These documents provide information on the health effects of exposure, the chemical’s toxicity and material for responding to a chemical incident. Conclusions: Occupational exposure to styrene is a risk factor for hearing loss, and styrene-exposed workers should be included in hearing loss prevention programs. 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