Kearns-Sayre syndrome, MELAS syndrome and Leber’s hereditary optic neuropathy are the metabolic disorders associated with the dysfunction of mitochondria in the cell. Ans. The following section consists of Biology Multiple Choice questions on Bacteria. ***Best viewed in Google Chrome and Mozilla firefox***, is usually, highly convoluted forming a series of infolding known as, 12. a. While the nuclear genome is linear, mitochondrial DNA is a small circular chromosome. Inner membrane contain more proteins/lipid ratio (by weight) than outer membrane, The protein/lipid ratio of inner membrane of mitochondria is 3:1 by weight, Cardiolipin is a diphosphatidylglycerol belongs to the class of glycerol-phospholipids. It is an important biological process for inheritance. c.       Sperm tail Thirteen of these genes provide instructions for making enzymes involved in oxidative phosphorylation. Cholesterol is absent in the inner membrane, c.       Cholesterol is present only in the inner membrane, d.      Cholesterol is present in both inner and outer membrane. Ans. a.      Mitochondrial outer membrane possess porins but they lack the usual beta barrel structure of the usual porins, b. mitochondrial inheritance . In contrast, mitochondria‐targeted ApaLI (lanes 7–10) eliminates type I mtDNA (MCQ 7: A; MCQ 18: B). a. 6, Chapter 5: Aerobic Respiration and Mitochondria, Page 174, 2. a.      Ribosome Freely transported through both outer and inner membrane of mitochondria, b. d.      Cannot be transported freely through outer and inner membrane of mitochondria. The number of mtDNA deletions in individual neurons in the substantia nigra is substantially increased in PD patients older than 65 years. (c) macromolecules breakdown. b.      Succinate dehydrogenase Closed circular. The energy (ATP) produced by these mitochondria are used by the flagella for their beating. 1. DNA polymerase γ, mtDNA helicase and mitochondrial single-stranded DNA-binding protein—the key replisome proteins, have evolved distinct structural features and biochemical properties. b. incomplete penetrance. Ke Liu, Ying Jin, Feng-Yan Zhang, Yan-Zhen Zhang, Xian-Qing Quan, Qing-Dian Han, Ling-Xiao Liu, Yun-Guo Liu, Shen-Jin Lv & Xiao-Ming Qu. b. Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to as the "powerhouses" of the cell. Understand the concept clearly by consistently practicing the Multiple Choice Questions and score well in your exams. Below, You will find a list of Biology MCQ Questions as per the latest prescribed syllabus. Which of the following membrane lipid constituent can be considered as the lipid marker of inner mitochondrial membrane? 11. d.      Mitochondria, (2). Cholesterol is completely absent in mitochondrial membrane, b. Both inner and outer mitochondrial membrane possess porin proteins Freely transported through the outer membrane of mitochondria The average size of mitochondria is about 1 to 4 µ and this size is best enough the resolve through light microscope. Inner membrane of Golgi apparatus, a. d) All of the above 20) In prokaryotes, the RNA primer from the lagging strand is removed and replaced by the DNA sequence. 16. ATP, NAD and CoA can be ___________. d.      Absence of genetic recombination in mtDNA. Enter your e-mail address. d.      Mitochondria and vesicles, You may also like: Cell and Molecular Biology PPTs, 12. c.       Large mitochondria in the call can split into two CEO @ T4Tutorials.com I welcome to all of you if you want to discuss about any topic. d.      Malate dehydrogenase. b.      Endoplasmic Reticulum b.      Cardiolipin During the last few years, mitochondrial DNA has attained much attention as a modulator of immune responses. (d). Mutations in mitochondrial DNA can lead to a variety of rare and poorly understood diseases. a.       NADH dehydrogenase b.      Endoplasmic Reticulum b. detect location of mRNA in cell . The study of cytosine methylation in mtDNA is limited. Freely transported through the outer membrane of mitochondria, ATP, NAD and Co-A can be freely transported through the outer mitochondrial membrane through the porin protein channels with beta-barrel structures, 11. 12. 13. Human mitochondrial genetics is the study of the genetics of human mitochondrial DNA (the DNA contained in human mitochondria).The human mitochondrial genome is the entirety of hereditary information contained in human mitochondria. b. True regarding Okazaki fragment – Biochemistry MCQ . Which of the following is a mobile electron carrier in the mitochondrial electron transport system? c.       Freely transported through the inner membrane of mitochondria Below, You will find a list of Biology MCQ Questions as per the latest prescribed syllabus. It is abundantly present in the inner mitochondrial membrane, where it contributes about 20% of the total lipid components. Mid piece Mitochondria in the human sperm cell are occupied at _________. Mitochondrial DNA is the small circular chromosomefound inside mitochondria. The only other place where cardiolipin can be found is the membrane of most bacterial cells. Chemical composition of both inner and outer membrane of mitochondria are same Characteristics of mitochondrial DNA (mtDNA) and results of research to date provide motivation to evaluate the relations between mtDNA copy number (mtDNAcn) and deletions (mtDNAdel) and couple fecundity. Which of the following cell organelle can be viewed by a light microscope? b.      RBC completely lack mitochondria Cyanide is a mitochondrial toxin. b.      Tay-sach syndrome In situ hybridisation: a. to detect rnRNA for protein products . DNB June 2011 – MCQ 19 . c.       Ceramide MCQ On DNA MCQ on Restriction enzymes. Correct answer : A. During the cell cycle, replication occurs at ‘S’ phase. Explore some important MCQs on mitochondria for NEET. a. Ans. (c). The fact that ApaLI needs translocation into mitochondria to act on mtDNA indicates that the transfected gene must have been integrated into nuclear DNA (MCQ 12: B) and that the protein is Sperm cell of insects completely lack mitochondria, 17. Mitochondrial DNA Beside their characteristic role as the powerhouse of the cell, mitochondria have another specificity: they are the only place outside the nucleus where DNA can be found. c.       Sperm cells of Insects completely lack mitochondria b.      NADPH dehydrogenase Thus, mutations in mtDNA were an obvious early target for analysis. c) DNA polymerase III possess 3'-5' exonuclease activity important for maintaining fidelity. a.      Mitochondrial outer membrane possess porins but they lack the usual beta barrel structure of the usual porins Due to common evolutionary origin, mitochondrial DNA shares various characteristic features with DNA of bacteria, as it consists of a remarkable number of unmethylated DNA as 2'-deoxyribose cytidine-phosphate-guanosine (CpG) islands. 5, Chapter 10 – Lipids: Membrane lipids, page: 349-351, 8. Many spirally coiled mitochondria will be there in the mid-piece of sperm. Mitochondrial DNA (mtDNA) is considered as one of the best marker tool for population biologists and evolutionary biologists. She was given the title “Mitochondrial Eve.” The mitochondrial function is … What is a mitochondrial DNA test? Ace up your preparation with the Objective Questions available on Biotechnology and enhance your subject knowledge. The mtDNA was recently found to exist CpG hypometh … Select the wrong statements from the following. (c). b.      Apoptosome 20. 1. Which of the following statement is true regarding the membrane system of mitochondria? Ans. Absence of genetic recombination in mtDNA. Until now, scientists studying these diseases in the lab could get rid of mutations by destroying the organelle’s DNA. codes for parts of mitochondrial enzymes (b). (d). The answer key is prepared with best of our knowledge. Inner membrane of Golgi apparatus b.      FADH Dehydrogenase The mechanism of action of cyanide is by inhibiting: a.      NADH dehydrogenase c.       Ubiquinone Which of the following statement about mitochondria is NOT true? Example for autonomous organelle(s): a.      Mitochondria The inner mitochondrial membrane has a) NADH dehydrogenase complex b) b-c1 complex c) cytochrome oxidase complex d) all of these Learn more. Oxysomes of F0-F1 particles occur on. d.      In all cells, one mitochondria will be exceptionally larger than others, (3). Ans. b.      Golgi apparatus (9). d.      Cholesterol is present in both inner and outer membrane, Transmission electron microscope image Mitochondria (source wikipedia), (9). c.       Mitochondria d.      Leber’s hereditary optic neuropathy. b.      Mitochondrial DNA can be easy isolated Ans. Ans. (b) protein synthesis. d.      Mitochondrial number may change in each cell of a species. Which of the following can be used as an enzyme marker for inner mitochondrial membrane? Outer membrane contain more proteins/lipid ratio (by weight) than inner membrane (b). c.       Isocitrate dehydrogenase Oxidative phosphorylation is a process that uses oxygen and simple sugars to create adenosine triphosphate (ATP), the cell's main energy source. Size and shape of mitochondria varies in a cell, b.      Mitochondria in the cell can fuse with one another, c.       Large mitochondria in the call can split into two, d.      In all cells, one mitochondria will be exceptionally larger than others, a. Both inner and outer mitochondrial membrane possess porin proteins, c.       Only the inner mitochondrial membrane possess porin proteins, d.      Many porin proteins which are structurally similar to the porins of bacterial cells are present in the outer membrane of mitochondria. C. Succinyl Co-A synthase d. 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